A Whole Blood Bactericidal Assay for Tuberculosis
نویسندگان
چکیده
منابع مشابه
TUBERCULOSIS Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children
Background: The diagnosis of latent Mycobacterium tuberculosis (MTB) infection with a tuberculin skin test (TST) in children is complicated by the potential influence of prior exposure to Bacille Calmette Geurin (BCG) vaccination or environmental mycobacteria. A whole blood assay has recently been developed to quantitatively measure interferon gamma (IFN-c) production by lymphocytes specific to...
متن کاملHRCT and whole-blood interferon-gamma assay for the rapid diagnosis of smear-negative pulmonary tuberculosis.
BACKGROUND Early diagnosis of active pulmonary tuberculosis (PTB) is critical for TB control, and difficult in patients with smear-negative sputum. OBJECTIVE We wanted to evaluate the usefulness of clinical findings, high-resolution computed tomography (HRCT), interferon-gamma-releasing assay (IGRA) and polymerase chain reaction (PCR) of sputum in the diagnosis of smear-negative PTB. METHOD...
متن کاملWhole Blood Interferon-Gamma Assay for Baseline Tuberculosis Screening among Japanese Healthcare Students
BACKGROUND The whole blood interferon-gamma assay (QuantiFERON-TB-2G; QFT) has not been fully evaluated as a baseline tuberculosis screening test in Japanese healthcare students commencing clinical contact. The aim of this study was to compare the results from the QFT with those from the tuberculin skin test (TST) in a population deemed to be at a low risk for infection with Mycobacterium tuber...
متن کاملHRCT and Whole-Blood Interferon- Assay for the Rapid Diagnosis of Smear-Negative Pulmonary Tuberculosis
Background: Early diagnosis of active pulmonary tuberculosis (PTB) is critical for TB control, and difficult in patients with smear-negative sputum. Objective: We wanted to evaluate the usefulness of clinical findings, high-resolution computed tomography (HRCT), interferon-releasing assay (IGRA) and polymerase chain reaction (PCR) of sputum in the diagnosis of smear-negative PTB. Methods: From ...
متن کاملA simplified assay for porphyrins in whole blood.
Recent investigations concerning the significance of porphyrins in erythrocytes indicate a need for a rapid quantitative assay, easily adaptable to routine clinical use. To till this need, we have developed a simplified procedure for the measurement of porphyrins (essentially protoporphyrin) in whole blood. Blood is stirred with acetone-ethyl acetate and the porphyrins are extracted with formic...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2001
ISSN: 0022-1899,1537-6613
DOI: 10.1086/319679